NUVIGIL, Wakefulness, and Narcolepsy
If you have narcolepsy and experience
excessive sleepiness (ES), NUVIGIL may be able to help improve your wakefulness.1
NUVIGIL can help improve wakefulness in patients who are very sleepy due to narcolepsy1
NUVIGIL is a prescription medicine used to improve wakefulness in adults who are
very sleepy due to narcolepsy. In a clinical trial, patients who took NUVIGIL experienced
significant improvement in wakefulness throughout the day, compared to patients
taking a sugar pill (placebo)1
- NUVIGIL was assessed using the Maintenance of Wakefulness Test (MWT), 4 times throughout the day
- The MWT is a measure of a person’s degree of sleepiness
- The measures were averaged between 9 AM and 3 PM2,3
For patients suffering from ES due to narcolepsy, NUVIGIL improves wakefulness throughout
NUVIGIL does not replace sleep and may not completely resolve your ES. Only you
and your doctor can decide if NUVIGIL is right for you, so make an appointment to
see your doctor today.
NUVIGIL typically does not affect patients' ability to sleep when they need to sleep1
Based on sleep studies that measure nighttime breathing and brain and muscle activity,
NUVIGIL does NOT interfere with sleep.1
5% of patients taking NUVIGIL reported trouble sleeping versus 1% of patients taking
a sugar pill (placebo).1
NUVIGIL has an established safety profile1
In clinical studies1:
- Most reported side effects were mild to moderate
- Common side effects of NUVIGIL were headache, nausea, dizziness, and trouble sleeping
- 7% of patients taking NUVIGIL stopped treatment due to side effects compared with
4% of patients taking a sugar pill (placebo)
NUVIGIL may cause serious side effects including a serious rash or a serious allergic
reaction that may affect parts of your body such as your liver or blood cells. Any
of these may need to be treated in a hospital and may be life-threatening.
Stop taking NUVIGIL and call your doctor right away or get emergency help if you
have any of these symptoms: skin rash, hives, sores in your mouth, or your
skin blisters and peels; swelling of your face, eyes, lips, tongue, or throat; trouble
swallowing or breathing; or fever, shortness of breath, swelling of the legs, yellowing
of the skin or whites of the eyes, or dark urine.
If you have a severe rash with NUVIGIL, stopping the medicine may not keep the rash
from becoming life-threatening or causing you to be permanently disabled or disfigured.
NUVIGIL is not approved for use in children for any medical condition. It
is not known if NUVIGIL is safe or if it works in children under the age of 17 years.
NUVIGIL is a federally controlled substance [C-IV] because it can be abused or lead
to dependence. Please use NUVIGIL only as directed and keep in a safe place to prevent
misuse and abuse.
NUVIGIL does not replace sleep and may not stop your ES completely. Only you and
your doctor can decide if NUVIGIL is right for you, so make an appointment to see
your doctor today.
While NUVIGIL is used to improve wakefulness in patients with narcolepsy, it is
not used to treat the sleep disorders themselves or their other symptoms or consequences.1