NUVIGIL, Wakefulness, and Narcolepsy

If you have narcolepsy and experience excessive sleepiness (ES), NUVIGIL may be able to help improve your wakefulness.1

NUVIGIL can help improve wakefulness in patients with excessive sleepiness due to narcolepsy1

NUVIGIL is a prescription medicine used to improve wakefulness in adults who experience excessive sleepiness (ES) due to narcolepsy. In a clinical trial, patients who took NUVIGIL experienced significant improvement in wakefulness throughout the day, compared to patients taking a sugar pill (placebo)1

  • NUVIGIL was assessed using the Maintenance of Wakefulness Test (MWT), 4 times throughout the day
  • The MWT is a measure of a person’s degree of sleepiness
  • The measures were averaged between 9 AM and 3 PM2,3

For patients suffering from ES due to narcolepsy, NUVIGIL improves wakefulness throughout the day1

NUVIGIL does not replace sleep and may not completely resolve your ES. Only you and your doctor can decide if NUVIGIL is right for you, so make an appointment to see your doctor today.

NUVIGIL typically does not affect patients' ability to sleep when they need to sleep1

Based on sleep studies that measure nighttime breathing and brain and muscle activity, NUVIGIL does NOT interfere with sleep.1

5% of patients taking NUVIGIL reported trouble sleeping versus 1% of patients taking a sugar pill (placebo).1

NUVIGIL has an established safety profile1

In clinical studies1:

  • Most reported side effects were mild to moderate
  • Common side effects of NUVIGIL were headache, nausea, dizziness, and trouble sleeping
  • 7% of patients taking NUVIGIL stopped treatment due to side effects compared with 4% of patients taking a sugar pill (placebo)

NUVIGIL may cause serious side effects including a serious rash or a serious allergic reaction that may affect parts of your body such as your liver or blood cells, and may result in hospitalization and be life-threatening. If you develop a skin rash, hives, sores in your mouth, blisters, swelling, peeling, or yellowing of the skin or eyes, trouble swallowing or breathing, dark urine, or fever, stop taking NUVIGIL and call your doctor right away or get emergency help.

NUVIGIL is not approved for children for any condition. It is not known if NUVIGIL is safe or if it works in children under the age of 17.

NUVIGIL is a federally controlled substance [C-IV] because it has the potential to be abused or lead to dependence. Please use NUVIGIL only as directed and keep in a safe place to prevent misuse and abuse.

NUVIGIL does not replace sleep and may not stop your ES completely. Only you and your doctor can decide if NUVIGIL is right for you, so make an appointment to see your doctor today.

While NUVIGIL is used to improve wakefulness in patients with narcolepsy, it is not used to treat the sleep disorders themselves or their other symptoms or consequences.1